Rosie O’Donnell fires back after being featured in Trump’s bizarre doctor AI video - The Independent

In July 2026, President Donald Trump shared a satirical video on Truth Social featuring deepfake portrayals of several high-profile Hollywood figures. The clip depicts the President dressed as a doctor who diagnoses these celebrities with a condition he terms Trump Derangement Syndrome (TDS).

What happened

The video utilizes AI-generated deepfakes of Rosie O’Donnell, John Leguizamo, Whoopi Goldberg, Edward Norton, Robert De Niro, and Julia Roberts. In the footage, these synthetic versions of the celebrities claim that their dislike of the President has rendered them dysfunctional, socially unpopular, and unable to maintain basic health. The deepfakes describe their supposed struggles with the ailment, while the President, acting as a physician, offers a satirical treatment plan that includes avoiding news media, daily prayer, and consuming Diet Coke. This incident is the latest development in a long-standing public feud between Trump and O’Donnell, which originated during a 2006 episode of The View. Following the release of the video, O’Donnell publicly criticized the President, suggesting the content reflects poorly on his mental state and calling for the invocation of the 25th Amendment. The President has previously characterized TDS as a legitimate medical condition during official events, and this video serves as a continuation of his efforts to frame political opposition as a clinical affliction.